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6 Drinks You Ought to By no means Combine With Blood Strain Medicines

greater by greater
September 20, 2025
Reading Time: 4 mins read
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6 Drinks You Ought to By no means Combine With Blood Strain Medicines



Should you take blood stress medicines like ACE inhibitors or beta-blockers, your physician has seemingly warned you to keep away from sure issues—together with some drinks.

Whereas blood stress medicines are usually efficient at reducing the chance of coronary heart assaults and strokes, sure drinks, like natural teas and juices, can intervene with how they work or set off undesirable unwanted effects.

Well being requested three cardiologists which drinks individuals shouldn’t drink whereas taking blood stress medicines. Right here’s what they needed to say.

Maybe probably the most well-known interplay is with grapefruit juice. In keeping with Sabrina Islam, MD, MPH, a heart specialist at Temple Well being and an affiliate professor of drugs on the Lewis Katz College of Drugs at Temple College, the drink inhibits an essential enzyme referred to as CYP3A4, which helps metabolize and break down many blood stress medicines.

“Ingesting extreme quantities of grapefruit juice can, in flip, result in larger ranges of those medicines within the bloodstream, which may trigger episodes of low blood stress,” Islam stated.

Different fruit juices, together with apple and citrus ones like orange, may additionally have an effect on how your physique absorbs and processes sure blood stress medicines, stated David Maron, MD, a heart specialist with the Preventive Cardiology Clinic at Stanford Drugs.

Should you take blood stress treatment and usually drink beer, wine, or cocktails, you might need to rethink. Alcohol can improve the consequences of sure blood stress medication, together with nondihydropyridine calcium channel blockers, alpha blockers, and beta-blockers, and will result in important drops in blood stress, Islam stated.

Alcohol may additionally worsen the unwanted effects of those medicines, together with dizziness, lightheadedness, fainting, and modifications in coronary heart charge, in keeping with the Nationwide Institute on Alcohol Abuse and Alcoholism.

On high of that, alcohol itself can elevate your blood stress—doubtlessly offsetting the advantages of your treatment. Simply greater than two drinks for males or a couple of for girls will be sufficient to have that impact, Maron stated.

Caffeine may also diminish the effectiveness of blood stress medicines. Analysis exhibits that beta-blockers and diuretics don’t work as nicely when caffeine enters the combination.

Maron recommends limiting caffeine consumption to lower than 400 milligrams (mg) per day, roughly the quantity in three cups of espresso. For reference, a cup of tea usually incorporates 35 mg of caffeine, whereas some power drinks comprise as much as 250 mg per serving.

Even in small quantities, licorice tea and drinks containing glycyrrhizin—a flavorful chemical present in licorice root—can dramatically improve blood stress and counteract the consequences of blood stress medicines, analysis exhibits.

This occurs as a result of glycyrrhizin inhibits a kidney enzyme that usually converts energetic cortisol into its inactive kind, cortisone, Maron defined. In consequence, cortisol can construct up within the physique. “Excessive cortisol ranges result in sodium retention, potassium loss, blood quantity enlargement, and hypertension,” he stated.

Many natural merchandise can alter how your physique processes, absorbs, or clears blood stress medication.

For instance, St. John’s wort can intervene with how medicines are metabolized within the liver, whereas ginseng and ephedra might elevate your coronary heart charge and blood stress, in keeping with Harlan Krumholz, MD, SM, a heart specialist with Yale Drugs.

“These interactions might blunt the treatment’s impact or trigger unwanted effects resembling dizziness, low potassium, or irregular coronary heart rhythms,” he stated.

Along with St. John’s wort, ginseng, and ephedra, Kumbolz recommends avoiding yohimbine and high-dose inexperienced tea extract.

Sure business vegetable juices can improve sodium ranges and trigger the physique to retain fluid. This buildup can pressure blood vessels and straight elevate blood stress, Krumholz stated. In consequence, high-sodium vegetable juices might cut back the advantages conferred by medicines like diuretics, ACE inhibitors, and angiotensin receptor blockers (ARBs).

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When that occurs, “individuals might expertise swelling, larger blood stress readings, or lowered effectiveness of their prescription drugs,” Krumholz stated.

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