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2025 NFL Odds Week 3: Strains, Spreads for all 16 Video games

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September 15, 2025
Reading Time: 6 mins read
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2025 NFL Odds Week 3: Strains, Spreads for all 16 Video games


Week 2 shall be within the operating for finest early-afternoon slate of the 12 months.

Now, Week 3 kicks off Thursday night time, because the Buffalo Payments host the Miami Dolphins.

Listed here are the strains for each Week 3 matchup at DraftKings Sportsbook as of Sept. 14.

This web page could include affiliate hyperlinks to authorized sports activities betting companions. For those who enroll or place a wager, FOX Sports activities could also be compensated. Learn extra about Sports activities Betting on FOX Sports activities.

(All occasions ET)

2025 NFL Week 3 Odds

THURSDAY, SEPT. 18

DOLPHINS @ BILLS (8:15 p.m., Prime Video)

Level unfold: Payments -12.5 (Payments favored to win by 12.5 factors or extra, in any other case Dolphins cowl)Moneyline: Payments -675 favorites to win (wager $10 to win $11.48 complete); Dolphins +490 underdogs to win (wager $10 to win $59 complete)Complete Over/Underneath: 49.5 factors scored by each groups mixed

SUNDAY, SEPT. 21

PACKERS @ BROWNS (1:00 p.m., FOX)

Level unfold: Packers -8.5 (Packers favored to win by 8.5 factors or extra, in any other case Browns cowl)Moneyline: Packers -410 favorites to win (wager $10 to win $12.44 complete); Browns +320 underdogs to win (wager $10 to win $42 complete)Complete Over/Underneath: 41.5 factors scored by each groups mixed

COLTS @ TITANS (1:00 p.m., CBS)

Level unfold: Colts -3 (Colts favored to win by 3 factors or extra, in any other case Titans cowl)Moneyline: Colts -155 favorites to win (wager $10 to win $16.45 complete); Titans +130 underdogs to win (wager $10 to win $23 complete)Complete Over/Underneath: 43.5 factors scored by each groups mixed

BENGALS @ VIKINGS (1:00 p.m., CBS)

Level unfold: Vikings -4.5 (Vikings favored to win by 4.5 factors or extra, in any other case Bengals cowl)Moneyline: Vikings -205 favorites to win (wager $10 to win $14.88 complete); Bengals +170 underdogs to win (wager $10 to win $27 complete)Complete Over/Underneath: 43.5 factors scored by each groups mixed

STEELERS @ PATRIOTS (1:00 p.m., CBS)

Level unfold: Steelers -1.5 (Steelers favored to win by 1.5 factors or extra, in any other case Patriots cowl)Moneyline: Steelers -115 favorites to win (wager $10 to win $18.70 complete); Patriots -105 underdogs to win (wager $10 to win $19.52 complete)Complete Over/Underneath: 44.5 factors scored by each groups mixed

Tom Brady breaks down Eagles’ win over Chiefs

RAMS @ EAGLES (1:00 p.m., FOX)

Level unfold: Eagles -4.5 (Eagles favored to win by 4.5 factors or extra, in any other case Rams cowl)Moneyline: Eagles -225 favorites to win (wager $10 to win $14.44 complete); Rams +185 underdogs to win (wager $10 to win $28.50 complete)Complete Over/Underneath: 45.5 factors scored by each groups mixed

JETS @ BUCCANEERS (1:00 p.m., FOX)

Level unfold: Buccaneers -7 (Buccaneers favored to win by 7 factors or extra, in any other case Jets cowl)Moneyline: Buccaneers -305 favorites to win (wager $10 to win $13.28 complete); Jets +245 underdogs to win (wager $10 to win $34.50 complete)Complete Over/Underneath: 45.5 factors scored by each groups mixed

RAIDERS @ COMMANDERS (1:00 p.m., FOX)

Level unfold: Commanders -6.5 (Commanders favored to win by 6.5 factors or extra, in any other case Raiders cowl)Moneyline: Commanders -278 favorites to win (wager $10 to win $13.60 complete); Raiders +225 underdogs to win (wager $10 to win $32.50 complete)Complete Over/Underneath: 47.5 factors scored by each groups mixed

FALCONS @ PANTHERS (1:00 p.m., FOX)

Level unfold: Falcons -3.5 (Falcons favored to win by 3.5 factors or extra, in any other case Panthers cowl)Moneyline: Falcons -180 favorites to win (wager $10 to win $15.56 complete); Panthers +150 underdogs to win (wager $10 to win $25 complete)Complete Over/Underneath: 44.5 factors scored by each groups mixed

TEXANS @ JAGUARS (1:00 p.m., CBS)

Level unfold: Jaguars -1.5 (Jaguars favored to win by 1.5 factors or extra, in any other case Texans cowl)Moneyline: Jaguars -115 favorites to win (wager $10 to win $18.70 complete); Texans -105 underdogs to win (wager $10 to win $19.52 complete)Complete Over/Underneath: 44.5 factors scored by each groups mixed

BRONCOS @ CHARGERS (4:05 p.m., CBS)

Level unfold: Chargers -2.5 (Chargers favored to win by 2.5 factors or extra, in any other case Broncos cowl)Moneyline: Chargers -142 favorites to win (wager $10 to win $17.04 complete); Broncos +120 underdogs to win (wager $10 to win $22 complete)Complete Over/Underneath: 45.5 factors scored by each groups mixed

SAINTS @ SEAHAWKS (4:05 p.m., CBS)

Level unfold: Seahawks -7.5 (Seahawks favored to win by 7.5 factors or extra, in any other case Saints cowl)Moneyline: Seahawks -345 favorites to win (wager $10 to win $12.90 complete); Saints +275 underdogs to win (wager $10 to win $37.50 complete)Complete Over/Underneath: 42.5 factors scored by each groups mixed

COWBOYS @ BEARS (4:25 p.m., FOX)

Level unfold: Bears -1.5 (Bears favored to win by 1.5 factors or extra, in any other case Cowboys cowl)Moneyline: Bears -120 favorites to win (wager $10 to win $18.33 complete); Cowboys +100 underdogs to win (wager $10 to win $20 complete)Complete Over/Underneath: 48.5 factors scored by each groups mixed

CARDINALS @ 49ERS (4:25 p.m., FOX)

Level unfold: Cardinals -1.5 (Cardinals favored to win by 1.5 factors or extra, in any other case 49ers cowl)Moneyline: Cardinals -118 favorites to win (wager $10 to win $18.47 complete); 49ers -102 underdogs to win (wager $10 to win $19.80 complete)Complete Over/Underneath: 43.5 factors scored by each groups mixed

CHIEFS @ GIANTS (8:20 p.m., NBC)

Level unfold: Chiefs -5.5 (Chiefs favored to win by 5.5 factors or extra, in any other case Giants cowl)Moneyline: Chiefs -250 favorites to win (wager $10 to win $14 complete); Giants +205 underdogs to win (wager $10 to win $30.50 complete)Complete Over/Underneath: 42.5 factors scored by each groups mixed

MONDAY, SEPT. 22

LIONS @ RAVENS (8:15 p.m., ABC/ESPN)

Level unfold: Ravens -6 (Ravens favored to win by 6 factors or extra, in any other case Lions cowl)Moneyline: Ravens -258 favorites to win (wager $10 to win $13.88 complete); Lions +210 underdogs to win (wager $10 to win $31 complete)Complete Over/Underneath: 51.5 factors scored by each groups mixed

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