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Home Health

Widespread Tongue Circumstances in Folks With HIV

greater by greater
July 6, 2025
Reading Time: 7 mins read
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Widespread Tongue Circumstances in Folks With HIV



Mouth and tongue lesions are sometimes one of many first signs of human immunodeficiency virus (HIV). HIV weakens your immune system, which might go away you vulnerable to sores and infections.

If left untreated, oral well being points could cause ache and different well being problems.

frank600 / Getty Photographs


Aphthous ulcers are small, yellow or grey sores with a purple border. They often seem on the tongue, cheeks, or contained in the lips. Mouth ulcers could make speaking and consuming painful, particularly in the event that they’re positioned below the tongue.

Mouth ulcers are sometimes a symptom of a weak immune system and stress. An estimated 50% of individuals with HIV expertise mouth and tongue ulcers due to their weakened immune programs. Dry mouth attributable to HIV and HIV drugs also can enhance your danger of mouth sores.

Sores will finally heal on their very own. Gentle ulcers will be handled with over-the-counter (OTC) numbing lotions that assist relieve ache and promote therapeutic. Extra extreme sores are handled with prescription corticosteroid mouthwashes or drugs.

Tunatura / Getty Photographs


Oral thrush is a kind of yeast an infection that causes patches of creamy white or yellow bumps that coat the tongue. These patches will be painless, or they might burn and bleed. Oral thrush also can have an effect on the tonsils, throat, cheeks, gums, and roof of the mouth. 

Oral thrush is the most typical mouth an infection that impacts folks residing with HIV. It is regular for yeast (a kind of fungus) to stay in your mouth. Nevertheless, when you have a weakened immune system as a consequence of HIV, it is simpler for this fungus to develop an excessive amount of, resulting in an infection. As a result of saliva within the mouth has antibodies to combat infections, HIV-related dry mouth additionally will increase your danger of oral thrush.

Prescription antifungal lozenges, drugs, or mouthwashes can deal with oral thrush. Nevertheless, oral thrush typically returns in case your immune system is simply too weak.

Oral furry leukoplakia (OHL).
Picture Credit score: U.S. Facilities for Illness Management and Prevention

Oral furry leukoplakia (OHL) causes white, hair-like patches on the edges of the tongue. It could actually additionally seem on the insides of the cheeks and decrease lip. These patches will be painless or trigger gentle ache. In additional extreme instances, you could lose your sense of style and expertise cold and hot sensitivity.

Folks with Epstein-Barr virus (EBV)—a standard herpes virus—can develop oral furry leukoplakia. EBV usually infects folks with extraordinarily weak immune programs, particularly these with HIV. EBV infections are additionally extra widespread in folks with untreated HIV.

Oral furry leukoplakia patches typically go away randomly, however there isn’t any treatment for the underlying Epstein-Barr virus. Therapy for OHL might embrace prescription anti-retroviral drugs to assist cut back patches and decrease EBV in your physique. Topical options, like podophyllin resin and retinoids, can be utilized to the tongue to take away patches. 

ardasavasciogullari / Getty Photographs


Herpes simplex virus kind 1 (HSV-1) could cause swollen, painful sores and blisters on the tongue. Blisters are additionally widespread on the lips and the roof of the mouth. Herpes blisters begin as small clusters of white or yellow fluid-filled bumps that finally burst into one bigger purple sore. 

Oral herpes impacts almost 20% of individuals with HIV. Dwelling with a weak immune system will increase your danger of getting extra oral herpes outbreaks, which might additionally unfold extra simply.

Herpes sores are very contagious and may unfold from kissing or sharing utensils. There is no such thing as a treatment for oral herpes, however prescription antivirals may help cut back therapeutic time and future outbreaks.

Sol Silverman, Jr., DDS / CDC


Oral warts appear to be small, laborious, skin-colored bumps or flat, white growths that resemble cauliflower. These painless warts typically seem on the tongue, lips, and within the mouth. On the tongue, warts often look grey or white and develop on the edges of the tongue or the lingual frenulum (the fold beneath your tongue).

Oral warts are attributable to totally different strains of the human papillomavirus (HPV). Folks with HIV usually tend to get HPV infections and oral warts due to their weakened immune system.

People who find themselves growing old with HIV or are doing extremely lively antiretroviral remedy (HAART) are additionally at an elevated danger of oral warts. Oral warts will be eliminated surgically or frozen off with cryosurgery. Nevertheless, warts can come again. 

MSC / Getty Photographs


Oral melanin hyperpigmentation appears like flat, brown patches on the tongue, lips, gums, cheeks, or roof of the mouth. This discoloration is attributable to elevated melanin (pores and skin pigment) within the mouth.

If in case you have HIV, the antiretroviral remedy (ART) medicine Retrovir (zidovudine), also referred to as AZT, could cause oral hyperpigmentation as a aspect impact. HIV-related oral hyperpigmentation would not often trigger issues or require remedy. Nevertheless, for those who’re frightened in regards to the look of hyperpigmentation, discuss together with your healthcare supplier. You might be able to swap to a special ART medicine.

Sustaining good oral hygiene may help forestall HIV tongue and mouth situations. Some dentist-approved ideas embrace:

Maintain your mouth clear: Brush your tooth for 2 minutes and floss twice day by day to take away meals, plaque, and dangerous micro organism in your mouth. 
Go to your dentist often: See your dentist not less than each six months for cleanings. If you do not have a dentist, ask your healthcare supplier or clinic for a referral. 
Take your HIV medicine: It is vital to take antiretroviral remedy drugs as directed and on schedule to cut back HIV in your physique and assist your immune system get better.
Keep away from dry mouth triggers: Restrict issues that may result in dry mouth, like smoking tobacco, consuming alcohol, and consuming salty meals.
Keep hydrated: Drink water typically, use a humidifier at bedtime, and think about using toothpaste or mouthwash designed to assist dry mouth.

If in case you have HIV, it is vital to see your supplier for those who expertise any modifications in your mouth or tongue. Mouth sores, dry mouth, and oral infections are sometimes indicators that HIV is progressing and the immune system is turning into weaker. Some HIV drugs also can make dry mouth worse, so your supplier might advocate a special remedy.

If left untreated, oral well being problems make you extra vulnerable to bacterial infections and septicemia (blood poisoning), which will be deadly with a weakened immune system. HIV-related tongue ulcers and dry mouth could cause ache that makes it laborious to speak, chew, and swallow. Tongue lesions also can put on down style buds and trigger lack of style.

Different warning indicators of HIV development that warrant a medical go to embrace:

FatigueFeverChillsSore throatMouth ulcersRashMuscle achesSwollen lymph nodesNight sweats

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